Feng Lili

Personal Information

-Department: College of Materials Science and Chemical Engineering

-Discipline: Materials Science and Engineering

-Professional Title: Associate Professor

-Post:

-Qualification: Master Supervisor

-Contact Information: +86-18845109691

-E-mail: fenglili@hrbeu.edu.cn

-Office Address:145 Nantong Street, Nangang Distinct, Harbin, 150001

-Education Experience:

2014/09-2019/06 Ph.D. in Materials Science and Engineering

Harbin Engineering University, Harbin

-Working Experience:

2019/08-2020/09 Research Fellow in Chemistry and Biological Chemistry

School of Physical and Mathematical Sciences,

Nanyang Technological University (NTU), Singapore;

2020/09-2021/08 Humboldt Research Fellow in Center for the Hybrid Nanostructures

Institute of Nanostructure and Solid State Physics (INF)

Universität Hamburg, Germany

2021.11-present Associate professor in Harbin Engineering University, Harbin

-Courses Undertaken:

Chemical engineering thermodynamics (Undergraduate major core courses)

Chemical machinery and equipment foundation (Undergraduate course)

Materials and chemical safety engineering (Elective courses for postgraduate students)

Scientific Research

-Research Fields: Inorganic nanomaterials, Innovative technology for cancer diagnosis and treatment

-Scientific Projects:

Principal Investigator, The tumor microenvironmental response mechanism of multi-metal nanozymes and the construction of an efficient treatment system

The National Natural Science Foundation of China, No. 52002091 2021-2023

Co-Principal Investigator, Study on the construction and performance of near infrared photoinduced oxygen compensation optical system for diagnosis and treatment

The National Natural Science Foundation of China, No. 51972075   2020-2023

Principal Investigator, Multimode imaging of bismuth-based nanocrystals with NIR-II fluorescence, CT and MR imaging

The Postdoctoral Science Foundation of China, No. 2020M670884 2020-2022

Principal Investigator, Near-infrared upconversion mesoporous hollow stannic oxide biophotocatalyst for concurrent PH-/H₂O₂-responsive O₂-evolving targeted synergetic cancer therapy

The Alexander von Humboldt Foundation of Germany 2020-2021

Principal Investigator, Fluorescence properties and bioimaging of rare earth doped bismuth-based nanocrystals

The Postdoctoral Program of Heilongjiang Provincial, No. LBH-Z19129 2019-2020

-Academic Exchanges

2019/08-2020/09 Research Fellow, Nanyang Technological University (NTU), Singapore;

2020/09-2021/08 Humboldt Research Fellow, Universität Hamburg, Germany;

Symposium Participant, Science, Engineering and Technology Vebleo webinar. Oral presentation: Tumor microenvironment activated glutathione self-depletion theranostic nanocapsules for imaging-directed synergistic cancer therapy. Sep 30, 2022

Symposium Participant, the 4th International Conference on MXenes, Nanjing, P. R. China. Pt decorated Ti₃C₂T_x MXene with NIR-II light amplified nanozyme catalytic activity for efficient phototheranostics. Aug 5~8, 2022

Symposium Participant, China Rare Earth Society 2022 Annual Conference, Neimenggu, P. R. China. The application of photoresponsive nano-functional materials in anticancer diagnosis and treatment.

Aug 17~19, 2022

Symposium Participant, the 12^th International Symposium on Phosphor Materials, Lanzhou, P. R. China. Oral presentation: Photoresponsive Functional Nanomaterials for Cancer Theranostics.  July 30~Aug 3, 2022

Awards & Honors

1. Special prize for Science and Technology of Heilongjiang Province Universities Dec 2021

2. Nomination Award for the "JINGBO Doctoral Dissertation Award in Chemical Engineering and Materials" of China Chemical Industry Society  Oct 2019

3. Humboldt Research Fellowship for Postdoctoral Research Fellow  July 2019

   Academic Achievements

   -Patents

4. The Preparation Method of NIR-Responsive Upconversion Mesoporous Tin Dioxide Nanocapsules for Cancer Theranostic

   Lili Feng, Lu Yang, Ruipeng Shi, Bin Liu, Shili Gai.

   Chinese Patent: ZL202111284507.0, Issued Dec 21, 2022

5. The Preparation Method Manganese Ion Doped Vanadium Diselide Nanosheets Responding to Near Infrared Light

   Lili Feng, Ruoxi Zhao, Piaoping Yang,Yanlin Zhu, Fei He, Yushan Dong, Jialing Zhou.

   Chinese Patent: ZL202210223296.8, Issued Feb 7, 2022

6. The Preparation Method of Hollow Mesoporous Tin Dioxide for Oxygen Vacancy in Tumor Diagnosis and Treatment

   Lili Feng, Ruoxi Zhao, Shili Gai, Lu Yang, Yanlin Zhu.

   Chinese Patent: 202111283045.0, Issued Nov 1, 2021

7. The Preparation Method of Compound Quantum Dots Used for Detecting Hydrogen Peroxide and Glucose Concentrations

   Lili Feng, Jialing Zhou, Piaoping Yang, Shili Gai, Fei He, Ruoxi Zhao.

   Chinese Patent: 202111512296.1, Issued Dec 7, 2021

8. The Preparation Method of Platinum Tin Bimetallic Nanoparticles with Catalytic Performance Enhanced by Near-Infrared Light

   Lili Feng, Yanlin Zhu, Piaoping Yang, Ruoxi Zhao, Fei He, He Ding, Chenghao Yu.

   Chinese Patent: 202210664711.3, Issued Jun 14, 2022

   -Published Works

   [1]. Yaofeng Zhou, Siyu Fan, Lili Feng*, Xiaolin Huang*, Xiaoyuan Chen*. Manipulating Intratumoral Fenton Chemistry for Enhanced Chemodynamic and Chemodynamic-Synergized Multimodal Therapy. Advanced Materials. 2021, 33(48), 2104223.

   [2]. Dingcheng Zhu, Lili Feng, Neus Feliu, Andreas Guse, Wolfgang J. Parak*. Stimulation of local cytosolic calcium release by photothermal heating for studying intra- and inter-cellular calcium waves. Advanced Materials. 2021, 33(24), 2170184.

   [3]. Jialing Zhou, Ruoxi Zhao, Yaqian Du, Shikai Liu, Wenting Li, Shili Gai, Fei He, Lili Feng*, Piaoping Yang*. A Si-CdTe Composite Quantum Dots Probe with Dual-Wavelength Emission for Sensitively Monitoring Intracellular H₂O₂. Advanced Functional Materials, 2022, 32(20), 2112083.

   [4]. Lili Feng, Bin Liu, Rui Xie, Dongdong Wang, Cheng Qian, Weiqiang Zhou, Jiawei Liu, Deblin Jana, Piaoping Yang*, and Yanli Zhao*. An Ultrasmall SnFe₂O₄ Nanozyme with Endogenous Oxygen Generation and Glutathione Depletion for Synergistic Cancer Therapy. Advanced Functional Materials, 2021, 31(5), 2006216.

   [5]. Lili Feng, Ruoxi Zhao, Lu Yang, Bin Liu, Shuming Dong, Cheng Qian, Jiawei Liu, and Yanli Zhao*. A Tumor-Specific NIR-Mediated Activatable Theranostic Nanoreactors for Self-Enhanced Multimodality Imaging and Cancer Phototherapy. ACS Nano, 2023, 17(2), 1622–1637.

   [6]. Shikai Liu, Linyang Fang, He Ding *, Yangyang Zhang, Wenting Li, Bin Liu, Shuming Dong, Boshi Tian, Lili Feng,* and Piaoping Yang*. An Alternative Strategy to Optimize Cerium Oxide for Enhanced X-Ray-Induced Photodynamic Therapy. ACS Nano, 2022, 16, 12, 20805-20819.

   [7]. Ruoxi Zhao, Yanlin Zhu, Jialing Zhou, Bin Liu, Yaqian Du, Shili Gai, Ruifang Shen, Lili Feng*, and Piaoping Yang*. Dual Glutathione Depletion Enhanced Enzyme Catalytic Activity for Hyperthermia Assisted Tumor Therapy on Semi-Metallic VSe₂/Mn-CS. ACS Nano, 2022, 16(7), 10904–10917.

   [8]. Yanlin Zhu, Zhao Wang, Ruoxi Zhao, Yiheng Zhou, Lili Feng*, Shili Gai*, and Piaoping Yang*. Pt Decorated Ti₃C₂T_x MXene with NIR-II Light Amplified Nanozyme Catalytic Activity for Efficient Phototheranostics. ACS Nano, 2022, 16(2), 3105-3118.

   [9]. Lili Feng, Shili Gai, Fei He, Piaoping Yang*, and Yanli Zhao*. Multifunctional Bismuth Ferrite Nanocatalysts with Optical and Magnetic Functions for Ultrasound-Enhanced Tumor Theranostics. ACS Nano, 2020, 11(13), 13144-13160.

   [10]. Jun Yang, Rui Xie, Lili Feng*, Bin Liu, Ruichan Lv, Chunxia Li, Shili Gai, Fei He, Piaoping Yang*, and Jun Lin*. Hyperthermia and Controllable Free Radicals Co-Enhanced Synergistic Therapy in Hypoxia Enabled by NIR-II Light Irradiation. ACS Nano, 2019, 14(6), 7245-7258.

   [11]. Lili Feng^#, Rui Xie^#, Chuanqing Wang, Shili Gai*, Fei He, Dan Yang, Piaoping Yang*, and Jun Lin*. Magnetic Targeting, Tumor Microenvironment Responsive Intelligent Nanocatalysts for Enhanced Tumor Ablation. ACS Nano, 2018, 12(11), 11000-11012 (Co-first author^#).

   [12]. Lu Yang, Haixia Zhu, Ruoxi Zhao, Zhijia Zhang, Bin Liu, Yanlin Zhu, Haijiang Gong, He Ding, Shili Gai, and Lili Feng*. Tumor Microenvironment Activated Glutathione Self-Depletion Theranostic Nanocapsules for Imaging-Directed Synergistic Cancer Therapy. Chemical Engineering Journal, 2022, 450, 138137.

   [13]. Lili Feng, Dan Yang, Shili Gai, Fei He, Guixin Yang, Piaoping Yang*, and Jun Lin*. Single Bismuth Tungstate Nanosheets for Simultaneous Chemo-, Photothermal, and Photodynamic Therapies Mediated by Near-Infrared Light. Chemical Engineering Journal, 2018, 351, 1147-1158.

   [14]. Lili Feng, Shili Gai, Fei He, Yunlu Dai, Chongna Zhong, Piaoping Yang*, and Jun Lin*. Multifunctional Mesoporous ZrO₂ Encapsulated Upconversion Nanoparticles for Mild NIR Light Activated Synergistic Cancer Therapy. Biomaterials, 2017, 147, 39-52.

   [15]. Boshi Tian, Yaqian Du, Shuming Dong, Lili Feng*, Bin Liu, Shikai, Liu, He Ding*, Shili Gai, Fei He, and Piaoping Yang*. NIR-Triggered Theranostic Nanoplatform with Controlled Release of HSP90 Inhibitor for Synergistic Mild-Photothermal and Enhanced Nanocatalytic Therapy Against Hypoxic Tumor. Small, 2022, 18(28), 2200786.